Synthesis, anticancer activity and photophysical properties of novel substituted 2-oxo-2H-chromenylpyrazolecarboxylates

…, G Saidachary, G Mallesham, B Sridhar, N Jain…

Index: Kumar, J. Ashok; Saidachary; Mallesham; Sridhar; Jain, Nishant; Kalivendi, Shashi Vardhan; Rao, V. Jayathirtha; Raju, B. China European Journal of Medicinal Chemistry, 2013 , vol. 65, p. 389 - 402

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Citation Number: 26

Abstract

Abstract 2-Oxo-2H-chromenylpyrazolecarboxylates (8a–h and 12a–zb) have been synthesized by [3+ 2] cycloaddition of 2H-chromenophenylhydrazones (7a–h and 11a–w) with diethyl/dimethylbut-2-ynedioates. Phenylchromeno [4, 3-c] pyrazol-4 (1H)-ones (13i–n) were prepared from corresponding phenylhydrazones (7a–h) with catalytic amount of piperidine in presence of pyridine as a solvent at 100 C. All the synthesized compounds ( ...

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