Molecular and Biochemical Parasitology 2012-08-01

Biochemical and molecular characterization of the pyrimidine biosynthetic enzyme dihydroorotate dehydrogenase fromToxoplasma gondii

Miryam Andrea Hortua Triana, My-Hang Huynh, Manuel F. Garavito, Barbara A. Fox, David J. Bzik, Vern B. Carruthers, Monika Löffler, Barbara H. Zimmermann, Miryam Andrea Hortua Triana, My-Hang Huynh, Manuel F Garavito, Barbara A Fox, David J Bzik, Vern B Carruthers, Monika Löffler, Barbara H Zimmermann

Index: Mol. Biochem. Parasitol. 184(2) , 71-81, (2012)

Full Text: HTML

Abstract

Graphical abstract Toxoplasma gondii dihydroorotate dehydrogenase is an essential mitochondrial enzyme that exhibits inhibitor sensitivities distinct from those of the human and Plasmodium falciparum enzymes.

Related Compounds

  • Orotic acid
  • L-Dihydroorotic a...
  • D-Hydroorotic Aci...

Related Articles:

Solubilization of gliadins for use as a source of nitrogen in the selection of bacteria with gliadinase activity.

2015-02-01

[Food Chem. 168 , 439-44, (2014)]

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

2010-01-01

[Chem. Res. Toxicol. 23 , 171-83, (2010)]

QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES.

2008-04-01

[Eur. J. Med. Chem. 43 , 714-40, (2008)]

Preparation and chromatographic evaluation of a newly designed steviol glycoside modified-silica stationary phase in hydrophilic interaction liquid chromatography and reversed phase liquid chromatography.

2015-04-03

[J. Chromatogr. A. 1388 , 110-8, (2015)]

High-throughput tandem mass spectrometry multiplex analysis for newborn urinary screening of creatine synthesis and transport disorders, Triple H syndrome and OTC deficiency.

2014-09-25

[Clin. Chim. Acta 436 , 249-55, (2014)]

More Articles...