Neoplasma 1986-01-01

Qualitative structure-activity relationships (QSAR) by the 1H NMR spectra of methylbenz[c]acridines.

K Kamata, N Motohashi

Index: Neoplasma 33(3) , 313-22, (1986)

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Abstract

The 1H NMR spectra of benz[c]acridine and its methyl derivatives (BAc) in CDCl3 have been measured. The total assignment of 1H NMR spectra and spin coupling constants of BAc were discussed. The good relationship between the delta delta (delta 2--delta 1) and epithelioma index (EI) have been gained. It was suggested that the utilization of exact NMR method in the screening of some chemical carcinogens can be adaptable.

Related Compounds

  • BENZ(C)ACRIDI...

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