Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl) butyl] piperidine-4-carboxamide derivatives as novel antihypertensive agents

S Watanuki, K Matsuura, Y Tomura, M Okada…

Index: Bioorganic and Medicinal Chemistry, , vol. 19, # 18 p. 5628 - 5638

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Citation Number: 6

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry. ... 7 We subsequently conducted high-throughput screening (HTS) using Astellas chemical library to identify a new series of T-type Ca 2+ channel blockers. ...

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