Acta Biochimica Polonica 2005-01-01

Single-stranded DNA-binding proteins (SSBs) -- sources and applications in molecular biology.

Józef Kur, Marcin Olszewski, Anna Długołecka, Paweł Filipkowski

Index: Acta Biochim. Pol. 52 , 569-574, (2005)

Full Text: HTML

Abstract

Single-stranded DNA-binding proteins (SSBs) play essential roles in DNA replication, recombination, and repair in bacteria, archaea and eukarya. The SSBs share a common core ssDNA-binding domain with a conserved OB (oligonucleotide/oligosaccharide binding) fold. This ssDNA-binding domain was presumably present in the common ancestor to all three major branches of life. In recent years, there has been an increasing interest in SSBs because they are useful for molecular biology methods and for analytical purposes. In this review, we concentrate on recent advances in the discovery of new sources of SSBs as well as certain aspects of their applications in analytical sciences.

Related Compounds

  • POLYTHYMIDYL...

Related Articles:

Single-stranded DNA-binding protein of Deinococcus radiodurans: a biophysical characterization.

2005-01-01

[Nucleic Acids Res. 33 , 1662-1670, (2005)]

Label-free emission assay of mercuric ions using DNA duplexes of poly(dT).

2011-06-28

[Dalton Trans. 40 , 6494-6499, (2011)]

Binding of the dimeric Deinococcus radiodurans single-stranded DNA binding protein to single-stranded DNA.

2010-09-28

[Biochemistry 49 , 8266-8275, (2010)]

A highly thermostable, homodimeric single-stranded DNA-binding protein from Deinococcus radiopugnans.

2006-12-01

[Extremophiles 10 , 607-614, (2006)]

More Articles...