Acta Pharmaceutica 2006-09-01

Preparation of 4-aminophenylacetic acid derivatives with promising antimicrobial activity.

Ahmed H Bedair, Fawzy M Ali, Ahmed M El-Agrody, Fathy A Eid, Mohammed A A El-Nassag, Gamal El-Sherbeny

Index: Acta. Pharm. 56(3) , 273-84, (2006)

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Abstract

Condensation of 4-aminophenylacetic acid with phthalic anhydride gave (dioxoisoindolin-2-yl)phenylacetic acid (1), which was employed as the key intermediate in the synthesis of title compounds 2-8. The products were characterized by analytical and spectral data (IR, 1H NMR, 13C NMR and mass spectra). Antimicrobial activities were studied and some of the compounds showed promising results.

Related Compounds

  • (4-Aminophenyl)ace...

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