Tetrahedron Letters

Microwave promoted synthesis of cycl [3.2. 2] azines in water via a new three-component reaction

S Gogoi, M Dutta, J Gogoi, RC Boruah

Index: Gogoi, Shyamalee; Dutta, Mandakini; Gogoi, Junali; Boruah, Romesh Chandra Tetrahedron Letters, 2011 , vol. 52, # 7 p. 813 - 816

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Citation Number: 12

Abstract

A microwave-promoted and base-catalyzed synthesis of cycl [3.2. 2] azines is accomplished in water via a three-component reaction (3-CR) of 2-picoline, α-bromoacetophenone and alkyne. The extension of the methodology to the synthesis of steroidal and carbocyclic cycl [3.2. 2] azine is also reported.

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