Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies

L Deng, J Diao, P Chen, V Pujari, Y Yao…

Index: Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4721 - 4734

Full Text: HTML

Citation Number: 45

Abstract

... Journal of Medicinal ... Address: Department of Pharmacology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030. ... Medicinal chemistry studies based on the structures of 1 and 2 have been carried out for the past decade.(8) Although most modifications resulted in ...

Related Articles:

Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies

[Deng, Lisheng; Diao, Jiasheng; Chen, Pinhong; Pujari, Venugopal; Yao, Yuan; Cheng, Gang; Crick, Dean C.; Prasad, B. V. Venkataram; Song, Yongcheng Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4721 - 4734]

More Articles...