Tetrahedron

A mild alternative to the use of benzyne in [4+ 2]-cycloaddition reactions

S Cossu, O De Lucchi

Index: Cossu, Sergio; De Lucchi, Ottorino Tetrahedron, 1996 , vol. 52, # 45 p. 14247 - 14252

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Citation Number: 8

Abstract

A synthetic protocol to assemble a benzene ring, mimicking the [4+ 2]-cycloaddition of benzyne is reported. The sequence of reactions is made up of simple and mild steps and overall it furnishes comparable or even better yields with respect to the direct addition of benzyne.

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