Journal of medicinal chemistry

Synthesis, structure− affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission …

R Xu, J Hong, CL Morse, VW Pike

Index: Ghiaci, Mehran; Asghari, Jila Synthetic Communications, 1999 , vol. 29, # 6 p. 973 - 979

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Citation Number: 12

Abstract

... Volume: Page: ... also been implicated in neuropsychiatric disorders, such as Alzheimer's disease, anxiety, and depression.(4-6). A reason ... blood−brain barrier (permeability parameter),(17) and susceptibility to metabolism.(8-10) Our synthetic strategies included ...

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