Novel potassium channel openers: synthesis and pharmacological evaluation of new N-(substituted-3-pyridyl)-N'-alkylthioureas and related compounds

T Takemoto, M Eda, M Hihara, T Okada…

Index: Journal of Medicinal Chemistry, , vol. 37, # 1 p. 18 - 25

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Citation Number: 18

Abstract

... d These compounds are disclosed in German Patent Offenleg 2557138 (Leo Pharmaceutical Products). analogues possessed more potent activity than compounds bearing a conformationally flexible alkyl chain. ... Page 5. 22 Journal of Medicinal Chemistry, 1994, Vol. ...