Journal of Allergy and Clinical Immunology 1990-01-01

Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride.

K M Venables, A J Newman Taylor

Index: J. Allergy Clin. Immunol. 85(1 Pt 1) , 55-8, (1990)

Full Text: HTML

Abstract

Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels of TCPA exposure. Measurements of TCPA in the test-cubicle air ranged from 1.3 to 961.1 micrograms/m3. The higher exposures provoked definite late or dual asthmatic responses. Smaller, but statistically significant, responses were observed at low exposures. The late asthmatic-response area had a linear relation to the logarithm of TCPA exposure, but the immediate asthmatic response was less closely related to exposure.

Related Compounds

  • Tetrachlorophthali...

Related Articles:

Allergic reactions to industrial chemicals.

1983-01-01

[Clin. Immunol. Rev. 2(1) , 1-58, (1983)]

Acid anhydrides.

1991-01-01

[Clin. Exp. Allergy 21 Suppl 1 , 234-40, (1991)]

Immunologic specificity of IgG against trimellityl-human serum albumin in serum samples of workers exposed to trimellitic anhydride.

1993-06-01

[J. Lab. Clin. Med. 121(6) , 792-6, (1993)]

Tetrachlorophthalic anhydride asthma: evidence for specific IgE antibody.

1983-01-01

[J. Allergy Clin. Immunol. 71(1 Pt 1) , 5-11, (1983)]

Interaction of smoking and atopy in producing specific IgE antibody against a hapten protein conjugate.

1985-01-19

[Br. Med. J. (Clin. Res. Ed.) 290(6463) , 201-4, (1985)]

More Articles...