Advanced Synthesis & Catalysis

Diazo Reagents in Copper (I)??Catalyzed Olefination of Aldehydes

H Lebel, M Davi

Index: Lebel, Helene; Davi, Michael Advanced Synthesis and Catalysis, 2008 , vol. 350, # 14-15 p. 2352 - 2358

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Citation Number: 19

Abstract

Abstract The olefination of aldehydes to synthesize unsaturated ketones, esters, amides and phosphonates using diazo reagents and triphenylphosphine in the presence of copper (I) iodide as catalyst, is described. Good to excellent E: Z selectivities as well as yields were obtained for a large variety of aliphatic, aromatic and heteroaromatic aldehydes. The reaction showed also an excellent functional group compatibility and aldehydes were ...

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