Notes-Fluoro Analogs of Prostigmine

S Shapiro, T Bazga, L Freedman

Index: Shapiro,S.L. et al. Journal of Organic Chemistry, 1960 , vol. 25, p. 2064 - 2066

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Citation Number: 5

Abstract

In particular, employment of a strongly meta orienting trifluoromethyl group2 evaluated replacement of the electronically similar trimethylammonium groupap4 of I. The steric effects of the trifluoromethyl group5 arid its incorporation into biologically active agents6 have been recently described. The meta relationship of the oxy function in I1 was indicated on pharmacological7 and chemica12+ 12 bases.