O-SpiroC-aryl glucosides as novel sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors
Baihua Xu, Binhua Lv, Yan Feng, Ge Xu, Jiyan Du, Ajith Welihinda, Zelin Sheng, Brian Seed, Yuanwei Chen, Baihua Xu, Binhua Lv, Yan Feng, Ge Xu, Jiyan Du, Ajith Welihinda, Zelin Sheng, Brian Seed, Yuanwei Chen
Index: Bioorg. Med. Chem. Lett. 19(19) , 5632-5, (2009)
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Abstract
Two series of O-spiro C-aryl glucosides have been synthesized and evaluated for inhibition of hSGLT1 and hSGLT2.
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