Scandium triflate catalyzed cycloaddition of imines with 1,1-cyclopropanediesters: efficient and diastereoselective synthesis of multi-substituted pyrrolidines.
Yan-Biao Kang, Yong Tang, Xiu-Li Sun
Index: Org. Biomol. Chem. 4(2) , 299-301, (2006)
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Abstract
A tandem ring-opening-cyclization reaction of cyclopropanes with imines in the presence of 5 mol% of scandium triflate was developed for the highly diastereoselective synthesis of multi-substituted pyrrolidines.
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