Tetrahedron

Eco-friendly atom-economical synthesis of 2-substituted-benzo [d] thiazoles and 2-substituted-benzo [d] oxazoles using 2-acylpyridazin-3 (2H)-ones

GH Sung, IH Lee, BR Kim, DS Shin, JJ Kim, SG Lee…

Index: Sung, Gi Hyeon; Lee, In-Hye; Kim, Bo Ram; Shin, Dong-Soo; Kim, Jeum-Jong; Lee, Sang-Gyeong; Yoon, Yong-Jin Tetrahedron, 2013 , vol. 69, # 17 p. 3530 - 3535

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Citation Number: 6

Abstract

Efficient and green syntheses of heterocycles are of great importance. In this work, we have demonstrated the synthesis of benzo [d] thiazoles and benzo [d] oxazoles using 2- acylpyridazin-3 (2H)-ones as acyl transfer agents under transition-metal-free and eco- friendly conditions. It is worthy to note that the reaction is efficient, green, and economical, and will find several applications in organic synthesis, medicinal chemistry, and industrial ...

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