Asymmetric N-heterocyclic carbene catalyzed addition of enals to nitroalkenes: controlling stereochemistry via the homoenolate reactivity pathway to access δ-lactams

NA White, DA DiRocco, T Rovis

Index: Journal of the American Chemical Society, , vol. 135, # 23 p. 8504 - 8507

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Citation Number: 49

Abstract

... Journal of the ... Soc. , 2013, 135 (23), pp 8504–8507. DOI: 10.1021/ja403847e. Publication Date (Web): May 28, 2013. Copyright © 2013 American Chemical Society. ... A brief screen of bases and base equivalents led us to our optimized conditions of 50 mol % sodium acetate (see ...

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