Mn (0)-Mediated Chemoselective Reduction of Aldehydes. Application to the Synthesis of α-Deuterioalcohols

T Jiménez, E Barea, JE Oltra, JM Cuerva…

Index: Jimenez, Tania; Barea, Elisa; Oltra, J. Enrique; Cuerva, Juan M.; Justicia, Jose Journal of Organic Chemistry, 2010 , vol. 75, # 20 p. 7022 - 7025

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Citation Number: 11

Abstract

A mild, simple, safe, chemoselective reduction of different kinds of aldehydes to the corresponding alcohols mediated by the Mn dust/water system is described. In addition to this, the use of D2O leads to the synthesis of α-deuterated alcohols and constitutes an efficient, inexpensive alternative for the preparation of these compounds.

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