Tetrahedron letters

New total synthesis of (±)-chuangxinmycin

K Kato, M Ono, H Akita

Index: Kato, Keisuke; Ono, Machiko; Akita, Hiroyuki Tetrahedron Letters, 1997 , vol. 38, # 10 p. 1805 - 1808

Full Text: HTML

Citation Number: 28

Abstract

(±)-4′-Iodoindolmycenate 6 was stereoselectively converted into the (±)-(2, 3)-syn-2- thioacetoxy ester 16 with retention of C2-stereochemistry in (±)-6. Palladium-catalysed cyclisation of indolyl iodide and the internal C2 thiol group of the substrate (±)-17 derived from (±)-16 gave the (±)-cis methyl ester 2 of natural chuangxinmycin (1).

Related Articles:

The chemistry of indoles. XVI. A convenient synthesis of substituted indoles carrying a hydroxy group, a halogeno group, or a carbon side chain at the 4-position via 4- …

[Chemical and Pharmaceutical Bulletin, , vol. 29, # 11 p. 3145 - 3157]

The chemistry of indoles. XXIV. Syntheses of 3-indoleacetic acid and 3-indoleacetonitrile having a halogeno group and a carbon functional group at the 4-position

[Somei; Kizu; Kunimoto; Yamada Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 9 p. 3696 - 3708]

A Synthesis of Arcyriacyanin A, an Unsymmetrically Substituted Indole Pigment of the Slime Mould by Palladium Catalyzed Cross-Coupling Reaction.

[Murase, Masayuki; Watanabe, Kazuhiro; Kurihara, Takayuki; Tobinaga, Seisho Chemical and Pharmaceutical Bulletin, 1998 , vol. 46, # 6 p. 889 - 892]

New total synthesis of (±)-chuangxinmycin

[Tetrahedron Letters, , vol. 38, # 10 p. 1805 - 1808]

New total synthesis of (±)-chuangxinmycin

[Tetrahedron Letters, , vol. 38, # 10 p. 1805 - 1808]

More Articles...