Frontiers in Bioscience 2007-01-01

Electrochemical studies oxidation of ciprofloxacin at nano-SnO2/PVS modified electrode and its interaction with calf thymus DNA.

Yuejuan Cai, Yuzhong Zhang, Shao Su, Suping Li, Yonghong Ni

Index: Front. Biosci. 12 , 1946-55, (2007)

Full Text: HTML

Abstract

In pH 6.0 phosphate buffer solutions (PBS), a glassy carbon electrode (GCE) modifying by nano-tin oxide/polyvinyl sulfonic potassium (nano-SnO2/PVS) exhibited an enhanced effectiveness for the oxidation of ciprofloxacin (CFX), which compared with a bare GCE or a nano-SnO2 modified electrode. In addition we also investigated the electrooxidation mechanism of the fluoroquinolone antibiotics (utilizing ciprofloxacin, ofloxacin, sparfloxacin and lomefloxacin) at the modified electrode. Furthermore, gel electrophoresis coupled with electrochemistry and spectra techniques were used to study the interaction of CFX and calf thymus DNA (ctDNA). These acquired data showed that the binding mode of CFX and DNA was mainly an intercalation mechanism.

Related Compounds

  • Poly(vinylsulfonic...

Related Articles:

Application of electrochemically prepared polypyrrole-polyvinyl sulphonate films to DNA biosensor.

2006-03-15

[Biosens. Bioelectron. 21(9) , 1777-83, (2006)]

Dynamic scale theory for characterizing surface morphology of layer-by-layer films of poly(o-methoxyaniline).

2004-05-01

[J. Nanosci. Nanotechnol. 4(5) , 548-52, (2004)]

Bioseparation of papain from Carica papaya latex by precipitation of papain-poly (vinyl sulfonate) complexes.

2013-09-01

[Protein Expr. Purif. 91(1) , 91-5, (2013)]

An amperometric biosensor for choline determination prepared from choline oxidase immobilized in polypyrrole-polyvinylsulfonate film.

2012-08-01

[Artif. Cells Blood Substit. Immobil. Biotechnol. 40(4) , 280-4, (2012)]

Surface plasmon fluorescence investigation of energy-transfer-controllable organic thin films.

2008-03-18

[Langmuir 24(6) , 2266-70, (2008)]

More Articles...