Effect of triterpenoid saponins from Bacopa monniera on scopolamine-induced memory impairment in mice.

Yun Zhou, Ling Peng, Wei-Dong Zhang, De-Yun Kong

Index: Planta Med. 75 , 568-74, (2009)

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Abstract

Three new saponins, bacopasides IX-XI (1- 3), together with their known analogues bacopaside I (4), bacopaside II (5), bacopasaponsin C (6), and bacopasaponsin D (7), were isolated from the whole plant of Bacopa monniera. Compounds 3, 4, and 6 showed nootropic activity when tested in the Morris water maze test and step-down test of scopolamine-induced memory impairment in mice.Copyright Georg Thieme Verlag KG Stuttgart. New York.