Bromination of deactivated aromatics: a simple and efficient method

…, R Saiganesh, KK Balasubramanian

Index: Rajesh; Somasundaram; Saiganesh; Balasubramanian Journal of Organic Chemistry, 2007 , vol. 72, # 15 p. 5867 - 5869

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Citation Number: 43

Abstract

Highly deactivated aromatic compounds were smoothly monobrominated by treatment with N-bromosuccinimide (NBS) in concentrated H2SO4 medium affording the corresponding bromo derivatives in good yields. Mild reaction conditions and simple workup provides a practical and commercially viable route for the synthesis of bromo compounds of deactivated aromatics.