Studies on Pyrazine Derivatives, XLVI: The Synthesis of New Pyrazine Derivatives with N′-(Pyrazine-2-carbonyl)-hydrazinecarbodithioic Acid Methyl Ester Usage

…, Z Zwolska, E Augustynowicz-Kopeć

Index: Gobis, Katarzyna; Foks, Henryk; Francuz, Joanna; Zwolska, Zofia; Augustynowicz-Kopec, Ewa Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 5 p. 977 - 986

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Citation Number: 5

Abstract

4-Ω-alkylsubstituted derivatives of 1, 2, 4-triazole-2-thiones 2–7 were obtained using the high reactivity of N′-(pyrazine-2-carbonyl)-hydrazinecarbodithioic acid methyl ester 1 towards amines. In the reaction with cysteamine 1, 3-thiazaethylene-1, 2, 4-triazole 8 formed. Aromatic amines and N-aminocycloalkylamines gave thiosemicarbazide derivatives 9–12 under the same conditions. The solution of sodium hydroxide caused the ...