Scandinavian Journal of Gastroenterology 2001-05-01

Hydrophilic and hydrophobic bile acids exhibit different cytotoxicities through cytolysis, interleukin-8 synthesis and apoptosis in the intestinal epithelial cell lines. IEC-6 and Caco-2 cells.

Y Araki, Y Fujiyama, A Andoh, F Nakamura, M Shimada, H Takaya, T Bamba

Index: Scand. J. Gastroenterol. 36(5) , 533-9, (2001)

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Abstract

Bile acids have been shown to exhibit varying degrees of cytotoxicity, depending on their hydrophobic-hydrophilic balance. We have recently reported the strong cytotoxicity of hyodeoxycholic acid (HDCA), and the aim of the present study is to investigate the mechanisms underlying the cytotoxicity of HDCA.

Related Compounds

  • Hyodeoxycholic aci...

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