Efficient microwave-assisted solvent-free synthesis of N-substituted aldimines
L Paquin, J Hamelin, F Texier-Boullet
Index: Paquin, Ludovic; Hamelin, Jack; Texier-Boullet, Francoise Synthesis, 2006 , # 10 p. 1652 - 1656
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Citation Number: 14
Abstract
Abstract Neat non-volatile amines react with various aromatic aldehydes in the absence of any catalyst, solid support, or solvent, to give imines after a reaction time of eight minutes under microwave irradiation by a clean and very efficient process (yields: 75-100%). In the case of volatile amine, methylamine, 1, 3-dimethylurea dispersed on montmorillonite K10 is used as an amine precursor to prepare the corresponding imines.
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