Method for the racemization of optically active amino acids

S Yamada, C Hongo, R Yoshioka…

Index: Yamada, Shigeki; Hongo, Chikara; Yoshioka, Ryuzo; Chibata, Ichiro Journal of Organic Chemistry, 1983 , vol. 48, # 6 p. 843 - 846

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Citation Number: 141

Abstract

A practical method for the racemization of optically active amino acids has been developed. A wide variety of optically active a-amino acids, including neutral amino acids, acidic amino acids, basic amino acids, and imino acids, could be racemized by heating in a medium of acetic acid at 80-100" C for 1 h in the presence of 0.05 molar equiv of an aliphatic or an aromatic aldehyde. The factors influencing the racemization were investigated. ...

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