Tetrahedron letters

Debromination of 8-bromo-2′-deoxyguanosine by methylene blue and visible light

L Venkatarangan, DH Yang, GA Epling, AK Basu

Index: Venkatarangan, Lata; Yang, Dan-Hui; Epling, Gary A.; Basu, Ashis K. Tetrahedron Letters, 1999 , vol. 40, # 8 p. 1441 - 1444

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Citation Number: 4

Abstract

Debromination of 8-bromo-2′-deoxyguanosine was accomplished in high yield under neutral conditions in aqueous methanol by irradiating with visible light in the presence of methylene blue as a sensitizer and triethylamine as an electron donor. The method can be extended for the debromination of other bromoaromatic compounds.

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