Dermatologica 1980-01-01

Detection of sclerosis-inducing glycosaminoglycan in the skin of an amine-induced experimental skin sclerosis.

H Ishikawa, A Yamakage, M Kitabatake, H Katayama, Y Saito

Index: Dermatologica 161(3) , 145-51, (1980)

Full Text: HTML

Abstract

The presence of sclerosis-inducing glycosaminoglycan in the skin was confirmed in an experimental skin sclerosis induced by a chemical compound. An experimental skin sclerosis was first produced in the mouse with bis(4-amino-3-methylcyclohexyl)methane. Out of glycosaminoglycans isolated from the slightly changed skin of this experimental skin sclerosis, the one having a heparan sulfate-like structure was able to again induce sclerotic skin changes in another mouse. The chemical composition of this sclerosis-inducing glycosaminoglycan was somewhat similar to that of the scleroderma-inducing glycosaminoglycan isolated previously from the urine of patients with systemic scleroderma.

Related Compounds

  • bis(4-amino-3-meth...

Related Articles:

Nephila clavipes spider dragline silk microstructure studied by scanning transmission X-ray microscopy.

2007-04-04

[J. Am. Chem. Soc. 129(13) , 3897-905, (2007)]

[Subacute toxicity of an amine-curing agent for epoxy resin].

1984-05-01

[Sangyo. Igaku. 26(3) , 197-204, (1984)]

Clinico-pathological changes induced in rats treated with amine-curing agent for epoxy resin, bis(4-amino-3-methylcyclohexyl)methane.

1986-05-01

[J. Toxicol. Sci. 11(2) , 79-93, (1986)]

[Scleroderma and scleroderma-like diseases caused by environmental pollutants].

1986-01-01

[Derm. Beruf Umwelt. 34(3) , 61-7, (1986)]

Pathomorphological changes in rat brain choroid plexus due to administration of the amine-curing agent, bis(4-amino-3-methylcyclohexyl)methane.

1990-01-01

[Virchows Arch. A. Pathol. Anat. Histopathol. 417(3) , 203-12, (1990)]

More Articles...