Journal of the American Chemical Society

The Synthesis of Heterocyclic Compounds by Means of Isothiourea Ethers

JF Deck, FB Dains

Index: Deck; Dains Journal of the American Chemical Society, 1933 , vol. 55, p. 4986,4987,4990

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Citation Number: 19

Abstract

//NR (HI synthesis of heterocyclic rings, the use of the thio ethers CHaS-C\ NHR (HI has been very limited. Wheeler and Johnson6 and their students have employed methyl isothiourea in the synthesis of pyrimidines, and in one instance a substituted quinazoline,'but only in this latter case did ring closure involve loss of the CH3S-grouping. A thiourea of the type RN= C-(SCH3) NHR contains two points of attack;(a) the SCH r group ...

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