The addition of nitrones to olefins. Fused bicyclic isoxazolidines

NA LeBel, ME Post, JJ Whang

Index: LeBel,N.A. et al. Journal of the American Chemical Society, 1964 , vol. 86, p. 3759 - 3767

Full Text: HTML

Citation Number: 85

Abstract

The oxidation of N-methyl-N-5-hexenylhydroxylamine with mercuric oxide and the condensation between 5-hexenal and N-methylhydroxylamine afforded cis-S-methyl-3-oxa- 2-azabicyclo [3.3. 0~ octane(2). Other bicyclic isoxazolidines have been synthesized by the condensation reaction employing unsaturated aldehydes and unsaturated ketones. The structures of these compounds were proved by hydrogenolysis and, in some cases, ...