Angewandte Chemie. International edition in English 2015-01-19

A general synthesis of fluoroalkylated alkenes by palladium-catalyzed Heck-type reaction of fluoroalkyl bromides.

Zhang Feng, Qiao-Qiao Min, Hai-Yang Zhao, Ji-Wei Gu, Xingang Zhang

Index: Angew. Chem. Int. Ed. Engl. 54(4) , 1270-4, (2015)

Full Text: HTML

Abstract

An efficient palladium-catalyzed Heck-type reaction of fluoroalkyl halides, including perfluoroalkyl bromides, trifluoromethyl iodides, and difluoroalkyl bromides, has been developed. The reaction proceeds under mild reaction conditions with high efficiency and broad substrate scope, and provides a general and straightforward access to fluoroalkylated alkenes which are of interest in life and material sciences. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Related Compounds

  • 1-bromoperfluorohe...

Related Articles:

In vitro cellular effects of perfluorochemicals correlate with their lipid solubility.

2000-05-01

[Am. J. Physiol. Lung Cell. Mol. Physiol. 278(5) , L1018-24, (2000)]

Triphenylsilyl as a protecting group in the synthesis of 1, 12-heterodisubstituted p-carboranes

2000-09-01

[J. Org. Chem. 65(5) , 1434-41, (2000)]

Intra-abdominal sepsis and perfluorocarbons: mechanism of protection.

1982-01-01

[Curr. Surg. 39(3) , 165-7, (1982)]

Perfluorochemicals as gastrointestinal contrast agents for MR imaging: preliminary studies in rats and humans.

2008-10-01

[AJR Am. J. Roentgenol. 148(6) , 1259-63, (1987)]

Value of brominated fluorocarbons for the radiographic diagnosis of small-bowel obstruction: comparison with other contrast agents in rats.

1993-08-01

[AJR Am. J. Roentgenol. 161(2) , 409-16, (1993)]

More Articles...