Organic Letters 2000-10-05

Efficient asymmetric synthesis of radicicol dimethyl ether: a novel application of ring-forming olefin metathesis.

R M Garbaccio, S J Danishefsky

Index: Org. Lett. 2 , 3127, (2000)

Full Text: HTML

Abstract

A concise, stereospecific synthesis of radicicol dimethyl ether is presented. The strategy relies on a convergent three-stage assembly of the 14-membered lactone which has, as a key transformation, a novel ring-forming metathesis reaction utilizing a vinyl epoxide.

Related Compounds

  • Methyl (R)-(-)-3-...

Related Articles:

A novel carbonyl reductase with anti-Prelog stereospecificity from Acetobacter sp. CCTCC M209061: purification and characterization.

2014-01-01

[PLoS ONE 9(4) , e94543, (2014)]

First total synthesis of grahamimycin A.

2000-10-20

[J. Org. Chem. 65 , 7221, (2000)]

A new synthesis of a key intermediate of beta-lactam antibiotics via diastereoselective alkylation of beta-hydroxy ester.

2000-12-01

[J. Org. Chem. 65 , 8372, (2000)]

A. Fischli, R. Scheffold, ed.

[Modern Synthetic Methods Salle+Sauerländer 2 , 269, (1980)]

More Articles...