FEBS Letters 1994-09-26

A herbicide antidote (safener) induces the activity of both the herbicide detoxifying enzyme and of a vacuolar transporter for the detoxified herbicide.

C Gaillard, A Dufaud, R Tommasini, K Kreuz, N Amrhein, E Martinoia

Index: FEBS Lett. 352(2) , 219-21, (1994)

Full Text: HTML

Abstract

In plants potentially toxic compounds are ultimately deposited in the large central vacuole. In this report we show that isolated barley mesophyll vacuoles take up the glucoside conjugate of the herbicide derivate [5-hydroxyphenyl]primisulfuron. Transport is stimulated by Mg-ATP and is distinct from that previously described for glutathione conjugates. Treatment of barley with different herbicide antidotes (safeners) revealed that the safener cloquintocet-mexyl doubles the vacuolar transport activities for both the glutathione and glucoside conjugates. Stimulation of the uptake of the metolachlor-glutathione conjugate was the result of an increased uptake velocity whereas the Km remained unaltered, suggesting that the higher activity was due to a higher expression of the transporter. These results indicate that modulation of vacuolar transport activities are an integral part of the detoxification mechanism of plants.

Related Compounds

  • 1,8-Naphthalic anh...

Related Articles:

1,8-Naphthalic anhydride antidote enhances the toxic effects of captan and thiram fungicides on Azospirillum brasilense cells.

1991-01-01

[Res. Microbiol. 142(9) , 1005-12, (1991)]

Sensitive enantiomeric separation of aliphatic and aromatic amines using aromatic anhydrides as nonchiral derivatizing agents.

1994-04-22

[J. Chromatogr. A. 666 , 485-491, (1994)]

Differential induction of cytochrome P450-mediated triasulfuron metabolism by naphthalic anhydride and triasulfuron.

1995-12-01

[Plant Physiol. 109(4) , 1483-90, (1995)]

Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes.

2003-01-01

[Mol. Med. 9(3-4) , 96-104, (2003)]

Cloning, functional expression, and characterization of CYP709C1, the first sub-terminal hydroxylase of long chain fatty acid in plants. Induction by chemicals and methyl jasmonate.

2005-10-28

[J. Biol. Chem. 280(43) , 35881-9, (2005)]

More Articles...