Synthetic Communications

Reaction of Oximes of α-Diketones with Diphosphorous Tetraiodide for Preparation of Oxadiazoles and Nitriles

VN Telvekar, BS Takale

Index: Telvekar, Vikas N.; Takale, Balaram S. Synthetic Communications, 2013 , vol. 43, # 2 p. 221 - 227,7

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Abstract

Oxadiazoles are important class of heterocycle utilized in variety of bioactive molecules [ 1–3 View all references ] including the metabotropic glutamate subtype 5 (mGlu5) receptor, [ 4 4. Roppe , J. ; Smith , ND ; Huang , D. ; Tehrani , L. ; Wang , B. ; Anderson , J. ; Brodkin , J. ; Chung , J. ; Jiang , X. ; King , C. ; Munoz , B. ; Varney , MA ; Prasit , P. ; Cosford , ND Discovery of novel heteroarylazoles that are metabotropic glutamate subtype 5 receptor antagonists with ...

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