Journal of Organic Chemistry 2001-04-20

An improved method for the palladium-catalyzed amination of aryl iodides.

M H Ali, S L Buchwald

Index: J. Org. Chem. 66 , 2560, (2001)

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Abstract

Aryl iodides are coupled with amines to give the corresponding arylamines in high yield in the presence of palladium, a suitable ligand, and NaOt-Bu. Functionalized aryl iodides give good yields of the corresponding arylamines when Cs(2)CO(3) is substituted as the base.

Related Compounds

  • 1-Iodo-3,5-dimethy...

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