Convenient Synthesis of N-Benzyl-N′-acyl-piperazines

…, G Palla, G Scapini, MR Cesaroni

Index: Gardini, G. P.; Palla, G.; Scapini, G.; Cesaroni, M. R. Synthetic Communications, 1982 , vol. 12, # 11 p. 887 - 890

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Abstract

Abstract The importance of N, N′ asymmetrically disubstituted piperazines in pharmaceutical and medicinal chemistry does not need to be emphasized. Such a basic moiety is present in a number of drugs belonging to different classes, and especially in those of the central and peripheral nervous system. In recent times the interest connected with piperazines appears to be a fast growing topic in drug research.