FEMS Microbiology Letters 2002-08-06

Metabolism of diphenylurea by a Marinobacter sp. isolated from a contaminated ephemeral stream bed in the Negev Desert.

Sebastian R Sørensen, Ziv Arbeli, Jens Aamand, Zeev Ronen

Index: FEMS Microbiol. Lett. 213(2) , 199-204, (2002)

Full Text: HTML

Abstract

A moderate halophilic Marinobacter sp. (designated strain DPUZ) able to metabolize 1,3-diphenylurea (DPU) was isolated from a contaminated ephemeral desert stream bed near an industrial complex in the northern part of the Negev Desert (Israel). Metabolism of DPU was accompanied by a transient accumulation of a metabolite identified as aniline using gas chromatography-mass spectrometry, thus indicating a metabolic pathway involving cleavage of the urea bridge between the phenyl structures. Aniline was further degraded without detection of other metabolites suggesting a complete degradation. Strain DPUZ grows at NaCl concentrations between 0.2 and 2.6 M with an optimum at 0.51 M. It grows at a temperature range between 20 and 40 degrees C with an optimum at 35 degrees C. This is the first study on bacterial metabolism of DPU.

Related Compounds

  • 1,3-Diphenylurea

Related Articles:

The structure-activity relationship of urea derivatives as anti-tuberculosis agents.

2011-09-15

[Bioorg. Med. Chem. 19 , 5585-95, (2011)]

Synthesis and evaluation of fluoroquinolone derivatives as substrate-based inhibitors of bacterial efflux pumps.

2008-11-01

[Eur. J. Med. Chem. 43 , 2453-63, (2008)]

Selectivity of kinase inhibitor fragments.

2011-07-28

[J. Med. Chem. 54 , 5131-43, (2011)]

Dispersive liquid-liquid microextraction for the determination of three cytokinin compounds in fruits and vegetables by liquid chromatography with time-of-flight mass spectrometry.

2013-11-15

[Talanta 116 , 376-81, (2013)]

More Articles...