Journal of Organic Chemistry 2005-03-18

Efficient preparation of nitrosoarenes for the synthesis of azobenzenes.

Beate Priewisch, Karola Rück-Braun

Index: J. Org. Chem. 70(6) , 2350-2, (2005)

Full Text: HTML

Abstract

[reaction: see text] Reaction conditions are described for the oxidation of anilines furnishing nitrosoarenes and the synthesis of unsymmetrically substituted azobenzenes. In a comparative study, the catalytic oxidation of methyl 4-aminobenzoate by hydrogen peroxide was investigated, and SeO(2) proved to be superior or equal to methyl trioxorhenium (MTO) and Na(2)WO(4), respectively. Nevertheless, the application of the inexpensive, environmentally friendly, Oxone in a biphasic system proved to be more efficient, and a variety of useful nitrosoarenes for the synthesis of azo compounds were prepared in high yield and purity on a large scale.

Related Compounds

  • Methyl 4-aminobenz...

Related Articles:

Tumor-preferential sustained drug release enhances antitumor activity of block copolymer micelles.

2014-08-01

[J. Drug Target. 22(7) , 619-28, (2014)]

Application of stripping voltammetry to trace lead analysis in intermediates and final products of syntheses of pharmaceuticals.

1996-05-01

[J. Pharm. Biomed. Anal. 14(7) , 765-71, (1996)]

In Silico Estimation of Skin Concentration Following the Dermal Exposure to Chemicals.

2015-12-01

[Pharm. Res. 32 , 3965-74, (2015)]

Total synthesis of the alkaloids martinelline and martinellic acid via a hetero Diels-Alder multicomponent coupling reaction.

2002-08-22

[Org. Lett. 4(17) , 2913-6, (2002)]

Topical drug delivery from thin applications: theoretical predictions and experimental results.

1990-10-01

[Pharm. Res. 7(10) , 1048-54, (1990)]

More Articles...