New methylene homologation method for cyclic ketones

…, C Sun, NK Lee, RF Henry, D Lee

Index: Liu, Huaqing; Sun, Chunrui; Lee, Nam-Kyu; Henry, Roger F.; Lee, Daesung Chemistry - A European Journal, 2012 , vol. 18, # 38 p. 11889 - 11893

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Citation Number: 2

Abstract

Ketones of carbocyclic and heterocyclic structures are pivotal for serving not only as a platform to develop new synthetic methods but also as building blocks for the synthesis of natural and medicinally important compounds.[1] One of the transformations involving cyclic ketones is a one-carbon insertion between the carbonyl carbon and its α-carbon (methylene homologation). Various forms of methylene homologation methodology have been ...