A new synthesis of lysophosphatidylcholines and related derivatives. Use of p-toluenesulfonate for hydroxyl group protection

R Rosseto, N Bibak, R DeOcampo, T Shah…

Index: Rosseto, Renato; Bibak, Niloufar; Hajdu, Joseph Organic and Biomolecular Chemistry, 2006 , vol. 4, # 12 p. 2358 - 2360

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Citation Number: 12

Abstract

A new stereoselective synthesis of lysophosphatidylcholines is reported. The synthesis is based upon (1) the use of 3-p-toluenesulfonyl-sn-glycerol to provide the stereocenter for construction of the optically active lysophospholipid molecule,(2) tetrahydropyranylation of

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