Organic letters

Nitroepoxides as Versatile Precursors to 1, 4-Diamino Heterocycles

A Vidal-Albalat, S Rodriguez, FV Gonzalez

Index: Vidal-Albalat, Andreu; Rodriguez, Santiago; Gonzalez, Florenci V. Organic Letters, 2014 , vol. 16, # 6 p. 1752 - 1755

Full Text: HTML

Citation Number: 12

Abstract

Nitroepoxides are easily transformed into 1, 4-diamino heterocycles such as quinoxalines and pyrazines by treatment with 1, 2-benzenediamines and ammonia, respectively. Additionally, related saturated heterocycles, such as piperazines and tetrahydroquinoxalines, can be accessed by treatment with 1, 2-diamines and a reducing agent. These transformations are efficient, provide access privileged, bioactive structures, ...

Related Articles:

Cu (II)-catalyzed synthesis of quinoxalines from o-phenylenediamines and nitroolefins

[Chen, Yongxin; Li, Kangning; Zhao, Mingming; Li, Yuanjiao; Chen, Baohua Tetrahedron Letters, 2013 , vol. 54, # 13 p. 1627 - 1630]

Saccharin as an Organocatalyst for Quinoxalines and Pyrido [2, 3-b] pyrazines Syntheses

[Lassagne, Frederic; Chevallier, Floris; Mongin, Florence Synthetic Communications, 2014 , vol. 44, # 1 p. 141 - 149]

Efficient, ecofriendly, and practical process for the synthesis of quinoxalines catalyzed by amberlyst-15 in aqueous media

[Liu, Ju-Yan; Liu, Jing; Wang, Jia-Di; Jiao, De-Quan; Liu, Hai-Wang Synthetic Communications, 2010 , vol. 40, # 14 p. 2047 - 2056]

A rapid synthesis of quinoxalines starting from ketones

[Padmavathy; Nagendrappa, Gopalpur; Geetha Tetrahedron Letters, 2011 , vol. 52, # 4 p. 544 - 547]

A new facile, efficient synthesis and structure peculiarity of quinoxaline derivatives with two benzimidazole fragments

[Mamedov, Vakhid A.; Zhukova, Nataliya A.; Syakaev, Victor V.; Gubaidullin, Aidar T.; Beschastnova, Tat'Yana N.; Adgamova, Dil'Bar I.; Samigullina, Aida I.; Latypov, Shamil K. Tetrahedron, 2013 , vol. 69, # 4 p. 1403 - 1416]

More Articles...