Cyanation of α, β-unsaturated enones by malononitrile in open air under metal-catalyst-free conditions

S Lin, Y Wei, F Liang

Index: Lin, Shaoxia; Wei, Ying; Liang, Fushun Chemical Communications, 2012 , vol. 48, # 79 p. 9879 - 9881

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Citation Number: 19

Abstract

The Michael reaction is one of the most fundamental approaches for the formation of new carbon–carbon and carbon–heteroatom bonds. 5 As a typical Michael donor, malononitrile would, no doubt, react with α,β-unsaturated enones, giving adduct 2 (Scheme 1a). 6 In our research on Michael-addition initiated cascade reactions, we disclose an unprecedented transformation into functionalized nitriles 3via formal Michael addition by using malononitrile as the ...