Nickel-catalyzed addition of P(O)-H bonds to propargyl alcohols: one-pot generation of phosphinoyl 1,3-butadienes.
Li-Biao Han, Yutaka Ono, Hideaki Yazawa
Index: Org. Lett. 7 , 2909, (2005)
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Abstract
[reaction: see text] Diphenylphosphine oxide and related P(O)H compounds react with propargyl alcohols at room temperature in the presence of a catalytic amount of Ni(0) complex and Ph(2)P(O)OH to produce high yields of phosphinoyl 1,3-dienes though an efficient in situ dehydration process.
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