Organic Letters 2006-12-07

One-pot synthesis of 2,3-dihydro-pyrrolopyridinones using in situ generated formimines.

Geoffrey Deguest, Alice Devineau, Laurent Bischoff, Corinne Fruit, Francis Marsais

Index: Org. Lett. 8 , 5889, (2006)

Full Text: HTML

Abstract

A novel one-pot methodology is described for the synthesis of functionalized pyrrolopyridinones using in situ generated formimines and an ortho-lithiated pyridinecarboxamide species. Depending on the reaction conditions, this procedure allows versatile access to aminomethylated pyridinecarboxamides, 2,3-dihydro-pyrrolopyridinones, or 1,1-dialkylated 2,3-dihydro-pyrrolopyridinone derivatives. [reaction: see text]

Related Compounds

  • 2,2,6,6-Tetramethy...

Related Articles:

Nano-Drugs Based on Nano Sterically Stabilized Liposomes for the Treatment of Inflammatory Neurodegenerative Diseases.

2015-01-01

[PLoS ONE 10 , e0130442, (2015)]

Oxidation of primary hydroxyl groups in chitooligomer by a laccase-TEMPO system and physico-chemical characterisation of oxidation products.

2016-01-01

[Carbohydr. Polym. 135 , 234-8, (2015)]

Reactivity of Amine/E(C6F5)3 (E = B, Al) Lewis Pairs toward Linear and Cyclic Acrylic Monomers: Hydrogenation vs. Polymerization.

2015-01-01

[Molecules 20 , 9575-90, (2015)]

More Articles...