Cationic antiprotozoal drugs. Trypanocidal activity of 2-(4'-formylphenyl) imidazo [1, 2-a] pyridinium guanylhydrazones and related derivatives of quaternary …

…, G Manikumar, B Mavunkel, A Biswas…

Index: Sundberg, Richard J.; Dahlhausen, Daniel J.; Manikumar, G.; Mavunkel, B.; Biswas, A.; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 298 - 307

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Citation Number: 20

Abstract

A series of quaternary 2-phenylimidazo [1, 2-a] pyridinum salts has been prepared and evaluated for antiparasitic activity. Primary attention was focused on derivatives with amido, substituted hydrazone, and heterocyclic functionality at the para position of the phenyl ...