European Journal of Cancer Prevention 1997-08-01

Chemopreventive effects of sandalwood oil on skin papillomas in mice.

C Dwivedi, A Abu-Ghazaleh

Index: Eur. J. Cancer Prev. 6(4) , 399-401, (1997)

Full Text: HTML

Abstract

The essential oil, emulsion or paste of sandalwood (Santalum album L) has been used in India as an ayurvedic medicinal agent for the treatment of inflammatory and eruptive skin diseases. In this investigation, the chemopreventive effects of sandalwood oil (5% in acetone, w/v) on 7,12-dimethylbenz(a)anthracene-(DMBA)-initiated and 12-O-tetradecanoyl phorbol-13-acetate(TPA)-promoted skin papillomas, and TPA-induced ornithine decarboxylase (ODC) activity in CD1 mice were studied. Sandalwood oil treatment significantly decreased papilloma incidence by 67%, multiplicity by 96%, and TPA-induced ODC activity by 70%. This oil could be an effective chemopreventive agent against skin cancer.

Related Compounds

  • Sandalwood oil

Related Articles:

Acne & rosacea: thinking outside the box.

2012-12-01

[Journal. of. Drugs in. Dermatology. 11(12) , 1400, (2012)]

Single-center, open-label study of a proprietary topical 0.5% salicylic acid-based treatment regimen containing sandalwood oil in adolescents and adults with mild to moderate acne.

2013-02-01

[Journal. of. Drugs in. Dermatology. 11(12) , 1403-8, (2012)]

TLC-bioautographic evaluation of in vitro anti-tyrosinase and anti-cholinesterase potentials of sandalwood oil.

2013-02-01

[Nat. Prod. Commun. 8(2) , 253-6, (2013)]

Preparative separation of α- and β-santalenes and (Z)-α- and (Z)-β-santalols using silver nitrate-impregnated silica gel medium pressure liquid chromatography and analysis of sandalwood oil.

2012-10-07

[Analyst 137(19) , 4564-70, (2012)]

Sandalwood oil prevent skin tumour development in CD1 mice.

1999-10-01

[Eur. J. Cancer Prev. 8(5) , 449-55, (1999)]

More Articles...