The Journal of Organic Chemistry

Cyclopropyl Sulfones1

WE TRUCE, LB LINDY

Index: Truce,W.E.; Lindy,L.B. Journal of Organic Chemistry, 1961 , vol. 26, p. 1463 - 1467

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Citation Number: 36

Abstract

A common approach to cyclopropyl derivatives5 involves a gamma elimination of hydrogen halide, where an &-hydrogen is activated by a carbonyl, nitrile, or other electron-withdrawing group. In view of the pseudo-acidity of the CY-hydrogen of sulfones6 this method was applied to y-halopropyl sulfones, using sodium amide,'which had been found to be a suitable base for converting y-chlorobutyronitrile into cyclopropyl cyanide. Treatment of y- ...