1',2'-seco-dideoxynucleosides as potential anti-HIV agents.

E Abushanab, M S Sarma

Index: J. Med. Chem. 32 , 76, (1989)

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Abstract

1',2'-seco-2',3'-Dideoxycytidine (12), -guanosine (14), -adenosine (16), and -inosine (18) were prepared from (R)-benzylglycidol as potential anti-HIV agents. When compared to ddAdo in protecting ATH8 cells, they were found to be inactive.