Tetrahedron Letters

A general method for the synthesis of indoles bearing a variety of substituents at the β-position, and its application to the synthesis of l-tryptophan

T Shono, Y Matsumura, T Kanazawa

Index: Shono, Tatsuya; Matsumura, Yoshihiro; Kanazawa, Takenobu Tetrahedron Letters, 1983 , vol. 24, # 12 p. 1259 - 1262

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Citation Number: 16

Abstract

Abstract A general synthetic method of β-substituted indoles such as indoleacetic acid, tryptamine and L-tryptophan has been exploited utilizing α-methoxylated amides, lactams, a carbamate, and sulfonamides, easily obtainable by an electrochemical method, as key intermediates.

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